The role of hypoxia-inducible factors in tumorigenesis
نویسندگان
چکیده
منابع مشابه
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Oxygen is vital to mammalian survival. Oxygen deprivation, defined as hypoxia, elicits adaptive responses in cells and tissues, a process regulated by proteins known as hypoxia-inducible factors (HIF). Animal studies have provided compelling data to demonstrate a pivotal role for the HIF pathway in the pathogenesis of acute kidney injury (AKI) that have led to initial human clinical trials exam...
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ژورنال
عنوان ژورنال: Cell Death & Differentiation
سال: 2008
ISSN: 1350-9047,1476-5403
DOI: 10.1038/cdd.2008.21